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Product Name
Rat E-Cadherin/CDH1/E-cad/CD324 (Fc Tag) recombinant protein
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Description
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity).
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Protein name
Cadherin-1
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Protein short names
LCAM; UM; ECAD; CDHE; L-CAM; MGC107495; E-CADHERIN; CD324; E-CAD; AA960649; UVO; ARC-1; CDH1
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Uniprot ID
Q9R0T4
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Gene Name
Cdh1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat CDH1 (Q9R0T4) (Met1-Ala713) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat CDH1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 931 amino acids and has a predicted molecular mass of 103.8 kDa. The apparent molecular mass of the protein is approximately 116 kDa in SDS-PAGE under reducing conditions
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Purity
> 75 % as determined by SDS-PAGE
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Validations
Rat E-Cadherin / CDH1 / E-cad / CD324 Protein (Fc Tag) SDS-PAGE
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