Anti-E Cadherin Rabbit antibody

Cat.#: 167545

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Product Information

  • Product Name
    Anti-E Cadherin Rabbit antibody
  • Documents
  • Description
    E Cadherin Rabbit polyclonal antibody
  • Tested applications
    WB, IP
  • Species reactivity
    Mouse, Rat
  • Alternative names
    Um; UVO; Ecad; ARC-1; E-cad; L-CAM; AA960649 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant protein of mouse E Cadherin
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000

    IP: 1/20

  • Validations

    Western blot detection of E Cadherin in Mouse brain lysates using E Cadherin Rabbit pAb(1:1000 diluted).Predicted band size:98(cleavages),135KDa.Observed band size: 80-120(cleavages),135KDa.

    Western blot detection of E Cadherin in Mouse brain lysates using E Cadherin Rabbit pAb(1:1000 diluted).Predicted band size:98(cleavages),135KDa.Observed band size: 80-120(cleavages),135KDa.

  • Background
    Swiss-Prot Acc.P09803.Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 .
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"