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Anti-E Cadherin (6B10) Mouse antibody

Cat.#: 168200

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Product Information

  • Product Name
    Anti-E Cadherin (6B10) Mouse antibody
  • Documents
  • Description
    E Cadherin (6B10) Mouse monoclonal antibody
  • Tested applications
    WB, IHC-P
  • Species reactivity
    Human, Mouse
  • Alternative names
    Arc 1; CADH1_HUMAN; Cadherin 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 324; CD324; CD324 antigen; cdh1; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependant adhesion protein; LCAM; Liver cell adhesion mole antibody
  • Isotype
    IgG1
  • Clonality
    Monoclonal
  • Formulation
    Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of E-Cadherin in T47D,HCT116,MDA-MB-468 and Caco-2 cell lysates using E-Cadherin mouse mAb(dilution 1:2000).Predicted band size:135kDa.Observed band size:135kDa.

    Western blot detection of E-Cadherin in T47D,HCT116,MDA-MB-468 and Caco-2 cell lysates using E-Cadherin mouse mAb(dilution 1:2000).Predicted band size:135kDa.Observed band size:135kDa.

    Immunohistochemical analysis of paraffin-embedded human tonsils using E-Cadherin (6B10) Mouse mAb.

    Immunohistochemical analysis of paraffin-embedded human tonsils using E-Cadherin (6B10) Mouse mAb.

    Western blot detection of E-Cadherin in Mouse embryos and HCT116 cell lysates using E-Cadherin mouse mAb(dilution 1:1000).Predicted band size:135kDa.Observed band size:135kDa.

    Western blot detection of E-Cadherin in Mouse embryos and HCT116 cell lysates using E-Cadherin mouse mAb(dilution 1:1000).Predicted band size:135kDa.Observed band size:135kDa.

  • Background
    Swiss-Prot Acc.P12830.Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
  • References
    • Antitumor and Antimetastasis Activities of Heparin-based Micelle Served As Both Carrier and Drug

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"