siRNA/miRNA Synthesis
RNA interference (RNAi) is a potent tool for gene silencing, playing a vital role in both biological research and therapeutic applications, particularly in addressing diseases that are difficult to treat, such as cancer. siRNA molecules bind to their target mRNA within the RISC complex, thereby preventing its activity, while miRNAs are involved in regulating mRNA degradation or translation, and their misregulation is associated with cancer development.
NovoPro specializes in providing tailored siRNA and miRNA synthesis services, ensuring top-notch quality through advanced synthesis methods and stringent quality assurance measures. Furthermore, NovoPro offers a range of chemically modified siRNAs designed for improved stability and effectiveness, as well as a variety of miRNA products including mimics, inhibitors, and controls, catering to a broad spectrum of research requirements.
- siRNA
- miRNA
| RNA | Purification | 5 nmol | 10 nmol | 20 nmol | >20 nmol | Delivery Time |
|---|---|---|---|---|---|---|
| siRNA | HPLC | $50.00 | $80.00 | $100.00 | Inquiry | 5 ~ 7 Business days |
| siRNA positive control | $7.00 | $12.00 | $18.00 | |||
| siRNA negative control | $7.00 | $12.00 | $18.00 | |||
| FAM labeled siRNA negative control | $15.00 | $22.00 | $30.00 |
Custom siRNA Package
| siRNA Package | Purification | Quantity | Price | Delivery Time | |
|---|---|---|---|---|---|
| siRNA | HPLC | 3 pairs | 10 nmol | $229.00 | 5 ~ 7 Business days |
| siRNA positive control | 1 pair | 5 nmol | |||
| siRNA negative control | 1 pair | 5 nmol | |||
| FAM labeled siRNA negative control | 1 pair | 5 nmol | |||
| RNA | Purification | 5 nmol | 10 nmol | 20 nmol | >20 nmol | Delivery Time |
|---|---|---|---|---|---|---|
| miRNA Mimic | HPLC | $50.00 | $80.00 | $100.00 | Inquiry | 5 ~ 7 Business days |
| miRNA Mimic negative control | $7.00 | $12.00 | $18.00 | |||
| miRNA inhibitor | $50.00 | $80.00 | $100.00 | |||
| miRNA Inhibitor negative control | $7.00 | $12.00 | $18.00 |
sgRNA Synthesis
CRISPR-Cas9 is a gene-editing technology that enables swift and precise modifications across diverse genomes, revolutionizing biological research. It traditionally involves Cas9, crRNA, and tracrRNA, but has been streamlined into a single-guide RNA (sgRNA) for ease of use. Synthetic sgRNA is favored for its convenience, as it arrives ready-to-use, eliminating the need for cloning, sequencing, or transcription. Moreover, it offers DNA-free editing options when paired with Cas9 mRNA or protein and permits the addition of chemical modifications for enhanced functionality.
| Service | Length | Quantity | Price | Specification |
|---|---|---|---|---|
| EcosgRNA | 97-103 nt | 3 nmol | $79 |
Research Purpose, Cost-effective |
| 5 nmol | $139 | |||
| 10 nmol | $289 | |||
| 50 nmol | $819 | |||
| 100 nmol | $1,279 | |||
| >100 nmol | Inquiry | |||
| ElitesgRNA | 3 nmol | $109 |
Research Purpose, Purity≥ 90% |
|
| 5 nmol | $199 | |||
| 10 nmol | $449 | |||
| 50 nmol | $1,279 | |||
| 100 nmol | $1,879 | |||
| >100 nmol | Inquiry |
*Modifications included: 2'-OMe and Phosphorothioate
RNA oligo Synthesis
Synthetic RNA is an essential research tool widely used in studying gene structure and function, gene editing, RNA drug development, RNA vaccine development, and more.
| RNA | Purification | 5 nmol | 10 nmol | 20 nmol | >20 nmol | Turnaround Time |
|---|---|---|---|---|---|---|
| ssRNA oligo (<23nt) | HPLC | $50.00 | $80.00 | $100.00 | Inquiry | 5 ~ 7 Business days |
| ssRNA oligo (23 ~ 40nt) | $70.00 | $100.00 | $160.00 | |||
| ssRNA oligo (41 ~ 60nt) | $110.00 | $160.00 | $220.00 | |||
| ssRNA oligo (61 ~ 80nt) | $160.00 | $220.00 | $260.00 | |||
| ssRNA oligo (81 ~ 100nt) | Inquiry | |||||
Modified RNA Synthesis (Fluorescent Labeling, Chemical Modification)
NovoPro provides customers with an extensive selection of synthetic RNA modification options, including fluorescent tagging, to cater to various needs. These modifications improve RNA cellular uptake, stability, and protection against nuclease degradation through techniques such as phosphorothioate, 2'-O-methyl, and 2'-fluoro modifications. Fluorescent labeling enables the visualization and tracking of RNA using fluorescence and confocal laser microscopy, which is valuable for applications like virus detection, disease diagnosis, and early cancer screening.