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Product Name
Human CD166/ALCAM (His Tag) recombinant protein
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Description
Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
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Protein name
CD166 antigen
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Protein short names
ALCAM; SC1; BEN; CD166; MEMD; MUSC; DM-GRASP; MGC27910; AI853494
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Uniprot ID
Q13740
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Gene Name
ALCAM; MEMD
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain (Met 1-Ala 526) of human ALCAM (NP_001618.2) was expressed, with the C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human ALCAM consists of 510 amino acids and has a calculated molecular mass of 57.4 kDa. As a result of glycosylation, rh ALCAM migrates as an approximately 60-70 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 98 % as determined by SDS-PAGE
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Activity
Immobilized human ALCAM-His at 10 μg/ml (100 μl/well) can bind mouse CD6-Fc (Cat:500293), The EC50 of mouse CD6-Fc (Cat:500293) is 0.1-0.22 μg/ml.
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Validations
Human ALCAM / CD166 Protein (His Tag) SDS-PAGE
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