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Product Name
ALCAM antibody
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Description
ALCAM Rabbit Polyclonal antibody. Positive WB detected in human liver tissue. Positive IHC detected in human breast cancer tissue, human colon cancer tissue. Observed molecular weight by Western-blot: 110 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human; other species not tested.
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Alternative names
ALCAM antibody; CD166 antibody; CD166 antigen antibody; FLJ38514 antibody; MEMD antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ALCAM recombinant protein (Accession Number: NM_001627). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:107956(ALCAM antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:107956(ALCAM antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human breast cancer using Catalog No:107956(ALCAM antibody) at dilution of 1:50 (under 40x lens)
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Background
Activated leukocyte cell adhesion molecule (ALCAM, also known as CD166) is a cell adhesion molecule that belongs to the immunoglobulin superfamily. It is involved in cell-cell adhesion through homophilic and heterophilic (to CD6) interactions. ALCAM is widely expressed in a variety of normal tissues. Altered ALCAM expression has been associated with the differentiation state and progression in some neoplasms including melanoma, prostate, colorectal, and breast cancers (PMID: 20461761; 18172759).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"