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Product Name
Rat CD166/ALCAM (His Tag) recombinant protein
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Description
Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system. May be involved in osteogenesis. May play an important role in the development of a variety of mesenchymal tissues (By similarity).
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Protein name
CD166 antigen
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Protein short names
BEN; CD166; ALCAM; SC1; MUSC; DM-GRASP; MGC27910; AI853494; MEMD
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Uniprot ID
O35112
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Gene Name
Alcam
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat ALCAM (O35112) (Met1-Lys527) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat ALCAM comprises 511 amino acids and predicts a molecular mass of 57.5 kDa. The apparent molecular mass of the recombinant protein is approximately 68-91 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 98 % as determined by SDS-PAGE
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Activity
Immobilized rat ALCAM-His at 10 μg/ml (100 μl/well) can bind mouse CD6-Fc (Cat:500293), The EC50 of mouse CD6-Fc (Cat:500293) is 0.08-0.18 μg/ml.
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Validations
Rat ALCAM / CD166 Protein (His Tag) SDS-PAGE
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