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Product Name
Anti-Phospho-EGFR (Tyr1173) Rabbit antibody
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Description
Phospho-EGFR (Tyr1173) Rabbit polyclonal antibody
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Tested applications
WB
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Species reactivity
Human
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Alternative names
Avian erythroblastic leukemia viral (v erb b) oncogene homolog;Cell growth inhibiting protein 40;Cell proliferation inducing protein 61;EGF R;EGFR;EGFR_HUMAN;Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: CSLDNPDp-YQQDFFP
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Clonality
Polyclonal
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Formulation
10mM PBS with 0.02% sodium azide 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500
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Validations
Western blot analysis of extracts of A549 cells, untreated or EGF-stimulated, using Phospho-EGF Receptor (Tyr1173) Rabbit pAb (upper,1:500 diluted) and EGF Receptor Antibody 201012-6H11 (lower,1:500 diluted).
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Background
Swiss-Prot Acc.P00533.EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"