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  • Anti-phospho-EGFR (Tyr1173) Rabbit antibody

Anti-phospho-EGFR (Tyr1173) Rabbit antibody

Cat.#: 167770

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Product Information

  • Product Name
    Anti-phospho-EGFR (Tyr1173) Rabbit antibody
  • Documents
  • Description
    phospho-EGFR (Tyr1173) Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC, IP
  • Species reactivity
    Human
  • Isotype
    IgG
  • Preparation
    Antigen: A synthetic phosphopeptide corresponding to residues surrounding Tyr1173 of human EGFR
  • Clonality
    Monoclonal antibody
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    IHC: 1/20

    ICC/IF: 1/20

    FC: 1/20

    IP: 1/20

  • Validations

    Western blot detection of phospho-EGFR (Tyr1173) in Hela,A549 cell lysates using phospho-EGFR (Tyr1173) Rabbit mAb(1:1000 diluted).Predicted band size:134kDa.Observed band size:175kDa.

    Western blot detection of phospho-EGFR (Tyr1173) in Hela,A549 cell lysates using phospho-EGFR (Tyr1173) Rabbit mAb(1:1000 diluted).Predicted band size:134kDa.Observed band size:175kDa.

  • Background
    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of coronavirus disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jun 2020]
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"