Anti-Phospho-EGFR (Tyr845) Rabbit antibody

Cat.#: 166662

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Product Information

  • Product Name
    Anti-Phospho-EGFR (Tyr845) Rabbit antibody
  • Documents
  • Description
    Phospho-EGFR (Tyr845) Rabbit polyclonal antibody
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    Avian erythroblastic leukemia viral (v erb b) oncogene homolog;Cell growth inhibiting protein 40;Cell proliferation inducing protein 61;EGF R;EGFR;EGFR_HUMAN;Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: CGAEEKEp-YHAEGGK
  • Clonality
    Polyclonal
  • Formulation
    10mM PBS with 0.02% sodium azide 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500

  • Validations

    Western blot analysis of extracts of A549 cells, untreated or EGF-stimulated, using Phospho-EGF Receptor (Tyr845) Rabbit pAb (upper,1:500 diluted) and EGF Receptor Antibody 201012-6H11 (lower,1:500 diluted).

    Western blot analysis of extracts of A549 cells, untreated or EGF-stimulated, using Phospho-EGF Receptor (Tyr845) Rabbit pAb (upper,1:500 diluted) and EGF Receptor Antibody 201012-6H11 (lower,1:500 diluted).

  • Background
    Swiss-Prot Acc.P00533.EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"