Rat VEGF / VEGFA / VEGF165 recombinant protein

Cat.#: 500590

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Product Information

  • Product Name
    Rat VEGF / VEGFA / VEGF165 recombinant protein
  • Documents
  • Description
    Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis.
  • Protein name
    Vascular endothelial growth factor A
  • Protein short names
    VEGF; VPF; VEGF-A; MVCD1; MGC70609; RP1-261G23.1
  • Uniprot ID
    P16612
  • Gene Name
    Vegfa; Vegf
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat VEGF 164 isoform (AAA41211.1) (Met 1-Arg 190) was expressed.
  • Protein Species
    Rat
  • Molecular weight
    The secreted recombinant rat VEGF164 consists of 164 amino acids and has a predicted molecular mass of 19.2 kDa. The apparent molecular mass of the rat VEGF164 is approximately 25 kDa in SDS-PAGE under reducing conditions due to glycosylation.
  • Purity
    > 86 % as determined by SDS-PAGE
  • Activity
    Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC).
    The ED50 for this effect is typically 1-10 ng/ml.
  • Validations

    Rat VEGF164 / VEGFA Protein SDS-PAGE

    Rat VEGF164 / VEGFA Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"