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Mouse VEGF / VEGFA / VEGF165 recombinant protein

Cat.#: 502886

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Product Information

  • Product Name
    Mouse VEGF / VEGFA / VEGF165 recombinant protein
  • Documents
  • Description
    Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis (By similarity).
  • Protein name
    Vascular endothelial growth factor A
  • Protein short names
    VEGF; VPF; VEGF-A; MVCD1; MGC70609; RP1-261G23.1
  • Uniprot ID
    Q00731
  • Gene Name
    Vegfa; Vegf
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse VEGF164 (isoform VEGF-1) (Q00731-2) (Met 1-Arg 190) was expressed and purified.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse VEGF164 consists of 164 amino acids and has a calculated molecular mass of 19.4 kDa. It migrates as an 24 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC).
    The ED50 for this effect is typically 0.8-4 ng/mL.
  • Validations

    Mouse VEGFA / VEGF164 Protein SDS-PAGE

    Mouse VEGFA / VEGF164 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"