NovoPro
Cart 2
  • Human VEGFA recombinant protein (Native)

Human VEGFA recombinant protein (Native)

Cat.#: 514912

Special Price 0.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human VEGFA recombinant protein (Native)
  • Documents
  • Description
    Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
  • Protein name
    Vascular endothelial growth factor A
  • Protein short names
    MVCD1,VEGF,VEGF165,VPF
  • Uniprot ID
    P15692-3
  • Gene Name
    Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human VEGF 183 isoform (P15692-3) (Met1-Arg209) was expressed.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human VEGF 183 isoform consists of 183 amino acids and has a predicted molecular mass of 21 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Activity
    Measured in a cell proliferation assay using human umbilical vein endothelial cells
    (HUVEC) (Conn, G. et al. 1990, Proc. Natl. Acad. Sci. USA 87:1323.). The ED50 for this effect is typically 10-50 ng/ml.
  • Validations

    Human VEGF 183 / VEGF-A Protein SDS-PAGE

    Human VEGF 183 / VEGF-A Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"