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Product Name
Human VEGF / VEGFA / VEGF165 recombinant protein
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Description
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.
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Protein name
Vascular endothelial growth factor A
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Protein short names
RP1-261G23.1; VEGF; VPF; VEGF-A; MVCD1; MGC70609
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Uniprot ID
P15692
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Gene Name
VEGFA; VEGF
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human VEGF 121 isoform b (P15692-9) (Met1-Asp147,with last 6 amino acids switch from CDKPRR to SLTRKD ) was expressed.
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Protein Species
Human
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Molecular weight
The recombinant human VEGF consists of 121 amino acids and has a predicted molecular mass of 14 kDa. The apparent molecular mass of the human VEGF121b is approximately 20 and 16 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
(28+70.8) % as determined by SDS-PAGE
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Validations
Human VEGF121b / VEGF-A Protein SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"