Rat Vegfa/Vegf recombinant protein

Cat.#: 518514

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Product Information

  • Product Name
    Rat Vegfa/Vegf recombinant protein
  • Documents
  • Description
    Vascular endothelial growth factor (VEGF/VEGF-A ) is originally known as vascular permeability factor (VPF). It belongs to the PDGF family with a cysteine-knot structure comprised of eight conserved cysteine residues, and reckoned as a potent mediator in the process of angiogenesis and vasculogenesis in either fetus or adult. VEGF is particularly expressed in supraoptic , paraventricular nuclei and the choroid plexus of the pituitary, and abundant in the corpus luteum of the ovary and in kidney glomeruli. The rat VEGF protein contains a putative 20 amino acids (aa) signal peptide, and alternative splicing of rat VEGF gene produces isoforms of 120, 144, 164 and 188 aa. Rat VEGF164 respectively displays 97% and 88% aa identity with that regions of mouse and human VEGF. VEGF can bind to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin, and play important roles in inducing endothelial cell proliferation, promoting cell migration, inhibiting apoptosis and inducing permeabilization of blood vessels.
  • Protein name
    vascular endothelial growth factor A(Vegfa)
  • Protein short names
    Vegf
  • Uniprot ID
    P16612-2
  • Source/Expression Host
    Yeast
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Rat Vegfa/Vegf Ala27-Arg190 is expressed.
  • Protein Species
    Rat
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Rat Vegfa/Vegf recombinant protein

    Rat Vegfa/Vegf recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"