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Marmoset IL12B/IL-12B (Fc Tag) recombinant protein

Cat.#: 501139

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Product Information

  • Product Name
    Marmoset IL12B/IL-12B (Fc Tag) recombinant protein
  • Documents
  • Description
    Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
  • Protein name
    Interleukin-12 subunit beta
  • Protein short names
    P40; CLMF; CLMF2; NKSF; IL12B; IMD28; NKSF2; IL-12B; IMD29; IL-12P40; IL12P40; RP23-388G23.1
  • Uniprot ID
    F7IQ84
  • Gene Name
    IL12B
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the marmoset IL12B (F7IQ84) (Met1-Asn328) was expressed with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Marmoset
  • Molecular weight
    The recombinant marmoset IL12B is a disulfide-linked homodimer. The reduced monomer comprises 547 amino acids and has a calculated molecular mass of 61.9 KDa.The apparent molecular mass of the protein is approximately 66 KDa in SDS-PAGE.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    1. Measured by its binding ability in a functional ELISA.
    2.Immobilized marmoset IL12B-Fc at 10 μg/mL (100 μL/well) can bind biotinylated human IL12RB1-His (Cat:501974). The EC50 of human IL12RB1-His is 0.66-1.53 μg/mL.
  • Validations

    Marmoset IL12B / IL-12B Protein (Fc Tag) SDS-PAGE

    Marmoset IL12B / IL-12B Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"