Human UCHL1 (His tag) recombinant protein

Human UCHL1 (His tag) recombinant protein

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Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 (UCHL1) belongs to the Peptidase C12 family. UCHL1 is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. UCHL1 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. UCHL1 is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. UCHL1 also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer of UCHL1 may have ATP-independent ubiquitin ligase activity.

ubiquitin C-terminal hydrolase L1(UCHL1)

P09936

E. coli

A DNA sequence encoding the Human UCHL1 Met1-Ala223 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.