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Product Name
Mouse UCHL1 (His Tag) recombinant protein
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Description
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
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Protein name
Ubiquitin carboxyl-terminal hydrolase isozyme L1
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Protein short names
AW822034; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; R75593; C88048; UCH-L1; HEL-117; UCHL-1; GAD; UCHL1
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Uniprot ID
Q9R0P9
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Gene Name
Uchl1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse UCHL1 (Q9R0P9) (Gln 2-Ala 223) was expressed, with a polyhistide tag at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse UCHL1 consisting of 233 amino acids and has a calculated molecular mass of 26.2 kDa. rm UCHL1 migrates as an approximately 29 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by the hydrolysis of UbiquitinAMC. The specific activity is >100 pmoles/min/μg.
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Validations
Mouse UCHL1 / PGP9.5 Protein (His Tag) SDS-PAGE
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