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Product Name
NKG2A antibody
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Description
NKG2A Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, HEK-293 cells, human liver tissue. Positive IHC detected in human lung cancer tissue. Observed molecular weight by Western-blot: 33kd
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human; other species not tested.
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Alternative names
CD159A antibody; KLRC1 antibody; NK cell receptor A antibody; NKG2 antibody; NKG2A antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of NKG2A recombinant protein (Accession Number: NM_007328). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:113197(KLRC1 antibody) at dilution of 1:800
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:113197(KLRC1 antibody) at dilution of 1:100 (under 10x lens)
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Background
KLRC1, also known as NKG2A (NKG2) and CD159A, is a single-pass type II membrane protein with extracellular C-type lectin domain. It belongs to the natural killer cell lectin-like receptor family, which is a group of transmembrane proteins preferentially expressed in NK cells. KLRC1 can form a heterodimer with CD94. The NKG2A/CD94 complex is an inhibitory receptor that recognizes HLA-E and is expressed by NK cells and a subset of T cells.
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