Anti-KLRC1 antibody

Cat.#: 141448

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Product Information

  • Product Name
    Anti-KLRC1 antibody
  • Documents
  • Description
    Rabbit Polyclonal to Human KLRC1
  • Tested applications
    WB, ELISA
  • Species reactivity
    Human NKG2A / NKG2 / CD159A / KLRC1
  • Alternative names
    CD159 antigen-like family member A antibody; CD159A antibody; CD159a antibody; C-lectin type II protein antibody; MGC13374 antibody; MGC59791 antibody; natural killer cell lectin antibody; natural killer group protein 2 antibody; NK cell receptor A antibody; NKG2 antibody; NKG2-1/B activating NK receptor antibody; NKG2A antibody; NKG2A antibody; NKG2-A/B type II integral membrane protein antibody; NKG2-A/B-activating NK receptor antibody; NKG2-A/NKG2-B type II integral membrane protein antibody; NKG2-A/NKG2-B type II integral membrane protein antibody; NKG2B antibody; NKG2 antibody; NKG2A antibody; CD159A antibody; NKG2A antibody; NKG2B antibody; CD159a antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Human NKG2A / NKG2 / CD159A / KLRC1 . NKG2A / NKG2 / CD159A / KLRC1 specific IgG was purified by Human NKG2A / NKG2 / CD159A / KLRC1 affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    WB: 5-20 μg/ml

    ELISA: 0.1-0.2 μg/mL

    This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human NKG2A / NKG2 / CD159A / KLRC1.

  • Validations

    Human NKG2A / NKG2 / CD159A / KLRC1 Western blot (WB) 15240

    Human NKG2A / NKG2 / CD159A / KLRC1 Western blot (WB) 15240

  • Background
    NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. This family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this fmaily are characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 contains 1 C-type lectin domain and forms a complex with another family member, KLRD1/CD94. It is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NKG2 functions as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"