Mouse NKG2A / NKG2 / CD159A / KLRC1 (His Tag) recombinant protein

Mouse NKG2A / NKG2 / CD159A / KLRC1 (His Tag) recombinant protein

• DataSheet
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NKG2, also known as NKG2A(CD159A), is a member of the killer cell lectin-like receptor family. This family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this fmaily are characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 contains 1 C-type lectin domain and forms a complex with another family member, KLRD1/CD94. It is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NKG2 functions as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Natural killer cell receptor NKG2A

NATURAL KILLER CELL LECTIN; C-LECTIN TYPE II PROTEIN; NK CELL RECEPTOR A; NKG2-A/B TYPE II INTEGRAL MEMBRANE PROTEIN; CD159 ANTIGEN-LIKE FAMILY MEMBER A; MGC13374; NKG2-A/NKG2-B TYPE II INTEGRAL MEMBRANE PROTEIN; NKG2-1/B ACTIVATING NK RECEPTOR; NKG2A; NATURAL KILLER GROUP PROTEIN 2; NKG2-A/B-ACTIVATING NK RECEPTOR; CD159A; NKG2; MGC59791; NKG2B

Q9WU31

Klrc1; Nkg2a

Human Cells

A DNA sequence encoding the mouse Klrc1 (AAD24969.1) (Ala94-Ile244) was expressed with a polyhistidine tag at the N-terminus.

Mouse

The recombinant mouse Klrc1 consists of 171 amino acids and predicts a molecular mass of 19.6 KDa. It migrates as an approximately 33-40 KDa band in SDS-PAGE under reducing conditions.

> 95 % as determined by SDS-PAGE