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Product Name
Human TNFRSF1B/TNFBR/TNFR2 (His tag) recombinant protein
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Description
Tumor necrosis factor receptor superfamily member 1B(TNFRSF1B) is expressed by the gene TNFRSF1B. The soluble form is produced from the membrane form by proteolytic processing. It can bind to TRAF2, and interacts with BMX. It can act as the receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha.
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Protein name
TNF receptor superfamily member 1B(TNFRSF1B)
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Protein short names
TNFBR; TNFR2
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Uniprot ID
P20333
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human TNFRSF1B/TNFBR/TNFR2 Lys288-Ser461 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human TNFRSF1B/TNFBR/TNFR2 (His tag) recombinant protein
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