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Product Name
Anti-Caspase-3 Rabbit antibody
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Description
Caspase-3 Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, IP
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Species reactivity
Human, Mouse, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human Caspase-3 p12
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Clonality
Polyclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500-1/1000
IHC: 1/100-1/500
ICC/IF: 1/50-1/200
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Validations
Immunofluorescent analysis of HeLa cells, using Caspase-3 p12 Antibody.
Western blot analysis of Caspase-3 p12 expression in HeLa cell treated with staurosporine lysate.
Immunohistochemical analysis of paraffin-embedded human kidney, using Caspase-3 p12 Antibody.
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Background
Swiss-Prot Acc.P42574.Caspase-3 is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP). Involved in the activation cascade of caspases responsible for apoptosis execution.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"