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Mouse CD80/B7-1 (Fc Tag) recombinant protein

Cat.#: 502695

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Special Price 272.2 USD

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Product Information

  • Product Name
    Mouse CD80/B7-1 (Fc Tag) recombinant protein
  • Documents
  • Description
    Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.
  • Protein name
    T-lymphocyte activation antigen CD80
  • Protein short names
    LY53; LY-53; MIC17; CD80; CD28L; BB1; B7; B7.1; B7-1; LAB7; TSA1; B71; CD28LG1; CD28LG
  • Uniprot ID
    Q00609
  • Gene Name
    Cd80; B7
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse CD80 (Q00609-1) extracellular domain (Met 1-Lys 245) was fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse CD80 consists of 449 amino acids and has a predicted molecular mass of 50.7 kDa.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    1. Measured by its binding ability in a functional ELISA.
    2. Immobilized human CTLA4 (cat: 503821) at 10 μg/mL (100 μl/well) can bind mouse CD80-Fc (cat: 502695), The EC50 of mouse CD80-Fc (cat: 502695) is 28 ng/mL.
  • Validations

    Mouse CD80 / B7-1 Protein (Fc Tag) SDS-PAGE

    Mouse CD80 / B7-1 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"