p38 MAPK antibody

Cat.#: 107443

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Product Information

  • Product Name
    p38 MAPK antibody
  • Documents
  • Description
    p38 MAPK Mouse Monoclonal antibody. Positive WB detected in human heart tissue, pig heart tissue. Observed molecular weight by Western-blot: 38-42 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human, Pig; other species not tested.
  • Alternative names
    CSAID binding protein antibody; CSBP antibody; CSBP1 antibody; CSBP2 antibody; CSPB1 antibody; EXIP antibody; MAP kinase 14 antibody; MAP kinase MXI2 antibody; MAP kinase p38 alpha antibody; MAPK 14 antibody; MAPK14 antibody; MAX interacting protein 2 antibody; Mxi2 antibody; p38 antibody; p38 MAPK antibody; p38ALPHA antibody; PRKM14 antibody; PRKM15 antibody; SAPK2A antibody
  • Isotype
    Mouse IgG2b
  • Preparation
    This antibody was obtained by immunization of p38 MAPK recombinant protein (Accession Number: NM_139012). Purification method: Protein A purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:1000-1:10000

  • Validations

    human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:107443(p38 MAPK Antibody) at dilution of 1:2000

    human heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:107443(p38 MAPK Antibody) at dilution of 1:2000

  • Background
    MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"