-
Product Name
Anti-p38 (5A1) Mouse antibody
- Documents
-
Description
p38 (5A1) Mouse monoclonal antibody
-
Tested applications
WB
-
Species reactivity
Human, Mouse, Rat, Monkey
-
Alternative names
CSAID Binding Protein 1; CSAID binding protein; CSAID-binding protein; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB 1; CSPB1; Cytokine suppressive anti inflammatory drug binding protein; Cytokine suppressive anti-inflammatory drug-bind antibody
-
Isotype
Mouse IgG1
-
Preparation
Antigen: Purified recombinant human P38 MAPK Pprotein fragments expressed in E.coli.
-
Clonality
Monoclonal
-
Formulation
Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
-
Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
WB: 1/500
-
Validations
Western blot analysis of extracts from C2C12,PC12,HepG2,COS7,C6,3T3 and Hela cell lysates using p38 MAPK mouse mAb (1:500 diluted).Predicted band size:40KDa.Observed band size:40KDa.
-
Background
Swiss-Prot Acc.Q16539.Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"