• Mouse Il1rl1/Ly84/St2/Ste2 (His tag) recombinant protein

Mouse Il1rl1/Ly84/St2/Ste2 (His tag) recombinant protein

Cat.#: 518065

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Product Information

  • Product Name
    Mouse Il1rl1/Ly84/St2/Ste2 (His tag) recombinant protein
  • Documents
  • Description
    ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.
  • Protein name
    interleukin 1 receptor-like 1(Il1rl1)
  • Protein short names
    Ly84; St2; Ste2
  • Uniprot ID
    P14719-2
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Il1rl1/Ly84/St2/Ste2 Ser27-Ala337 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Il1rl1/Ly84/St2/Ste2 (His tag) recombinant protein

    Mouse Il1rl1/Ly84/St2/Ste2 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"