-
Product Name
Canine IL-4/IL4 / Interleukin-4 recombinant protein
- Documents
-
Description
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes (By similarity).
-
Protein name
Interleukin-4
-
Protein short names
RP23-188H3.4; BSF-1; MGC79402; IL4; IL-4; BCGF1; BSF1; BCGF-1
-
Uniprot ID
O77762
-
Gene Name
IL4
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the canine IL4 (O77762) (His 25-His 132) was expressed, with an initial Met at the N-terminus.
-
Protein Species
Canine
-
Molecular weight
The recombinant canine IL4 consists of 109 amino acids and has a calculated molecular mass of 13 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 12-14 KDa band.
-
Purity
> 96 % as determined by SDS-PAGE
-
Activity
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells.
The ED50 for this effect is typically 5-30 ng/ml. -
Validations
Canine IL4 / Interleukin-4 Protein SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"