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Product Name
IL-4 antibody
- Documents
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Description
IL-4 Mouse Monoclonal antibody. Positive IHC detected in human tonsillitis tissue. Positive WB detected in Jurkat cells, Transfected HEK-293 cells. Observed molecular weight by Western-blot: 18 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
B cell stimulatory factor 1 antibody; Binetrakin antibody; BSF 1 antibody; BSF1 antibody; IL 4 antibody; IL4 antibody; IL-4 antibody; interleukin 4 antibody; PS1TP5BP1 antibody
- Immunogen
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of IL-4 recombinant protein (Accession Number: NM_000589). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107401(IL4 antibody) at dilution of 1:1000
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107401(IL4 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107401(IL4 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107401(IL4 Antibody) at dilution of 1:50 (under 40x lens)
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Background
IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.
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