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  • Human IL-4/IL4 / Interleukin-4 recombinant protein

Human IL-4/IL4 / Interleukin-4 recombinant protein

Cat.#: 500224

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Product Information

  • Product Name
    Human IL-4/IL4 / Interleukin-4 recombinant protein
  • Documents
  • Description
    Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
  • Protein name
    Interleukin-4
  • Protein short names
    BCGF-1; BSF1; RP23-188H3.4; BSF-1; MGC79402; IL-4; BCGF1; IL4
  • Uniprot ID
    P05112
  • Gene Name
    IL4
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human IL4 isoform 1 (P05112-1) (His 25-Ser 153) was expressed and purified, with an initial Met.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IL4 consisting of 130 amino acids and migrates with an apparent molecular mass of 15 kDa as predicted.
  • Purity
    > 92 % as determined by SDS-PAGE
  • Activity
    Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is 0.05-0.2 ng/mL.
    The specific activity of Recombinant Human IL-4 is approximately 3.2 × 104 IU/μg
  • Validations

    Human IL4 / Interleukin-4 Protein SDS-PAGE

    Human IL4 / Interleukin-4 Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"