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Product Name
Canine IL-2 (147 Cys/Ser) recombinant protein
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Description
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
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Protein name
Interleukin-2
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Protein short names
DN-144H19.3; LYMPHOKINE; IL2; TCGF; IL-2
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Uniprot ID
Q29416
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Gene Name
IL2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of canine IL2 (Q29416) (Ala 21-Thr 155, 147Cys/Ser) was expressed, with an initial Met at the N-terminus.
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Protein Species
Canine
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Molecular weight
The recombinant canine IL2 consists of 136 amino acids and has a calculated molecular mass of 15.6 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 15 kDa band.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
1. Measured by its binding ability in a functional ELISA.
2. Immobilized recombinant Canine IL2 (cat:500337) at 10 μg/mL can bind recombinant human IL2Ra-Fc (Cat:503136) with a linear range of 0.3125-20 μg/ml. -
Validations
Canine Interleukin-2 / IL-2 Protein (147 Cys/Ser) SDS-PAGE
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