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IL2 antibody

Cat.#: 107390

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Product Information

  • Product Name
    IL2 antibody
  • Documents
  • Description
    IL2 Mouse Monoclonal antibody. Positive WB detected in Jurkat cells. Positive IHC detected in human tonsillitis tissue, human breast cancer tissue. Observed molecular weight by Western-blot: 18 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    Aldesleukin antibody; IL 2 antibody; IL2 antibody; interleukin 2 antibody; lymphokine antibody; T cell growth factor antibody; TCGF antibody
  • Isotype
    Mouse IgG2a
  • Preparation
    This antibody was obtained by immunization of IL2 recombinant protein (Accession Number: NM_000586). Purification method: Protein A purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107390(IL2 Antibody) at dilution of 1:1000

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107390(IL2 Antibody) at dilution of 1:1000

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107390(IL2 Antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieved with Tris-EDTA buffer, pH9.0

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107390(IL2 Antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieved with Tris-EDTA buffer, pH9.0

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107390(IL2 Antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieved with Tris-EDTA buffer, pH9.0

    Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107390(IL2 Antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieved with Tris-EDTA buffer, pH9.0

  • Background
    IL2 is a secreted cytokine involved in the operation and regulation of immune system. IL2 plays a pivotal role in T-cell activation and effector functions, including T cell proliferation, interferon-γproduction and cytotoxicity. IL2 can stimulate the propagation of lymphocytes and induce the cytotoxic T lymphocytes and lymphokine-activated killer cells for tumor cells. IL2 also influences memory T cell homeostasis through the regulation of memory T cell numbers and enhances major histocompatibility complex II (MHC II) expression on tumor cells.
  • References
    • Wang C, Chen K, Xia Y. N-acetylcysteine attenuates ischemia-reperfusion-induced apoptosis and autophagy in mouse liver via regulation of the ROS/JNK/Bcl-2 pathway. PloS one. 9(9):e108855. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"