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Product Name
Mouse IL-2 recombinant protein
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Description
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
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Protein name
Interleukin-2
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Protein short names
TCGF; IL2; IL-2; DN-144H19.3; LYMPHOKINE
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Uniprot ID
P04351
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Gene Name
Il2; Il-2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the soluble form of mouse IL2 (P04351) (Ala 21-Gln 169) was expressed, with an initial Met at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse IL2 consists of 150 amino acids and has a calculated molecular mass of 17.4KDa. It migrates as an approximately 19 kDa in SDS-PAGE under reducing conditions.
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Purity
> 92 % as determined by SDS-PAGE
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Activity
1. Measured by its ability to bind recombinant human IL2Ra-Fc (Cat:503136) in a functional ELISA.
2. Measured in a cell proliferation assay using CTLL2. The ED50 for this effect is typically 0.2-1.0 ng/mL. -
Validations
Mouse Interleukin-2 / IL-2 Protein SDS-PAGE
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