-
Product Name
Human IL-2 (L35M, L36S, C142A) recombinant protein
- Documents
-
Description
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
-
Protein name
Interleukin-2
-
Protein short names
LYMPHOKINE; DN-144H19.3; TCGF; IL2; IL-2
-
Uniprot ID
Q0GK43
-
Gene Name
IL2
-
Source/Expression Host
Yeast
-
Expression Plasmid/cDNA
A DNA sequence encoding human IL2 (NP_000577.2) (Ala 21-Thr153, Leu 35 Met, Leu 36 Ser, Cys 142 Ala) was expressed.
-
Protein Species
Human
-
Molecular weight
The recombinant human IL2 consists of 133 amino acids and predicts a molecular mass of 15.4 kDa. It migrates as an approximately 15 kDa band in SDS-PAGE under reducing conditions.
-
Purity
> 85 % as determined by SDS-PAGE
-
Activity
Measured in a cell proliferation assay using CTLL2 cells.
The ED50 for this effect is typically 0.35-1.4 ng/mL. -
Validations
Human IL2 / Interleukin-2 Protein (L35M, L36S, C142A) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"