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Product Name
Human UCHL3 (His tag) recombinant protein
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Description
Ubiquitin Carboxyl-Terminal Hydrolases (UCHs) are a family of cysteine hydrolases. They catalyze the hydrolysis of amides, thioesters and esters, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin. Up regulation of UCHL3 is associated with uterine cervical neoplasms. UCHL3 is implicated in age related cognitive disorders. UCHL3 also promotes adipogenesis and insulin signaling. In mice, UCHL3 knockout have been shown to be resistant to diet-induced obesity.
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Protein name
ubiquitin C-terminal hydrolase L3(UCHL3)
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Uniprot ID
P15374
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human UCHL3 Met1-Ala230 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human UCHL3 (His tag) recombinant protein
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