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Product Name
Human SEMA4D/C9orf164/CD100/SEMAJ (Fc tag) recombinant protein
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Description
Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
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Protein name
semaphorin 4D(SEMA4D)
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Protein short names
C9orf164; CD100; SEMAJ
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Uniprot ID
Q92854
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human SEMA4D/C9orf164/CD100/SEMAJ Met22-Arg734 is expressed with a Fc tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human SEMA4D/C9orf164/CD100/SEMAJ (Fc tag) recombinant protein
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