Anti-Semaphorin 4D/SEMA4D/CD100 antibody

Cat.#: 104497

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Product Information

  • Product Name
    Anti-Semaphorin 4D/SEMA4D/CD100 antibody
  • Documents
  • Description
    Mouse monoclonal to Semaphorin 4D/SEMA4D/CD100
  • Tested applications
    FCM
  • Species reactivity
    Human SEMA4D / CD100
  • Alternative names
    C9orf164 antibody; CD100 antibody; CD100 antibody; coll-4 antibody; coll-4 antibody; FLJ33485 antibody; FLJ34282 antibody; FLJ39737 antibody; M-sema-G antibody; SEMA4D antibody; Semacl2 antibody; SEMAJ antibody; Semaphorin 4D antibody; FLJ46484 antibody; MGC169138 antibody; MGC169141 antibody; CD100 antibody; SEMAJ antibody; coll-4 antibody; C9orf164 antibody; M-sema-G antibody; CD100 antibody; Semaj antibody; Semcl2 antibody; coll-4 antibody; Semacl2 antibody; Sema4d antibody; Semaj antibody; Semaphorin 4D antibody; Semcl2 antibody; XXyac-YM68G7.1 antibody
  • Immunogen
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SEMA4D / CD100 (rh SEMA4D / CD100; Q92854-1; Met1-Arg734) and conjugated with PE under optimum conditions, the unreacted PE was removed.
  • Clonality
    Monoclonal
  • Formulation
    Aqueous solution containing 0.5% BSA and 0.09% sodium azide
  • Storage instructions
    This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
    Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
  • Applications
    FCM
  • Validations

    Semaphorin 4D / SEMA4D / CD100 Antibody (PE), Mouse MAb, Flow cytometric

    Semaphorin 4D / SEMA4D / CD100 Antibody (PE), Mouse MAb, Flow cytometric

    Profile of peripheral blood lymphocytes analyzed by flow cytometry.

  • Background
    Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"