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  • Human CD44/LHR/MDU2/MDU3/MIC4 (Fc tag) recombinant protein

Human CD44/LHR/MDU2/MDU3/MIC4 (Fc tag) recombinant protein

Cat.#: 518015

Special Price 265.0 USD

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Product Information

  • Product Name
    Human CD44/LHR/MDU2/MDU3/MIC4 (Fc tag) recombinant protein
  • Documents
  • Description
    CD44 is a cell-surface receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. A large number of CD44 isoforms can be generated by the insertion of different combinations of at least nine exons. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Furthermore, an increasing quantity of evidence suggests that CD44 has various functions related to inflammatory disease. CD44 deficiency induces severe liver injury. CD44-hyaluronate mediates in lymphocyte T and monocyte adhesion to the endothelium, stimulates proinflammatory cytokine release from macrophages and participates in dedifferentiation phenotype of smooth muscle cells from contractile state to synthetic one.
  • Protein name
    CD44 molecule (Indian blood group)(CD44)
  • Protein short names
    LHR; MDU2; MDU3; MIC4
  • Uniprot ID
    P16070
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human CD44/LHR/MDU2/MDU3/MIC4 Gln21-Pro220 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human CD44/LHR/MDU2/MDU3/MIC4 (Fc tag) recombinant protein

    Human CD44/LHR/MDU2/MDU3/MIC4 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"