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Anti-CD44 (2H12) Mouse antibody

Cat.#: 168205

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Special Price 123.9 USD

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Product Information

  • Product Name
    Anti-CD44 (2H12) Mouse antibody
  • Documents
  • Description
    CD44 (2H12) Mouse monoclonal antibody
  • Tested applications
    WB, IP, ICC/IF, IHC-P
  • Species reactivity
    Human
  • Alternative names
    LHR; BA-1; CD 44; CD44; CD44 antigen; CD44 molecule (Indian blood group); CD44 molecule; CD44_HUMAN; CDw44; Cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; Epican; Extracellular matrix receptor III; GP90 lymphocyte hom antibody
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant human CD44 protein fragments expressed in E.coli.
  • Clonality
    Monoclonal
  • Formulation
    PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of CD44 in HUVEC cell lysates using CD44 mouse mAb(dilution 1:1000).Predicted band size:82kDa.Observed band size:80kDa.

    Western blot detection of CD44 in HUVEC cell lysates using CD44 mouse mAb(dilution 1:1000).Predicted band size:82kDa.Observed band size:80kDa.

    Immunoprecipitation analysis of Hela cell lysates using CD44 mouse mAb.

    Immunoprecipitation analysis of Hela cell lysates using CD44 mouse mAb.

    Immunofluorescent analysis of HeLa cells fixed with 1% Paraformaldehyde and using CD44 Mouse mAb (168205,dilution 1:200,green). DAPI was used to stain nucleus(blue).

    Immunofluorescent analysis of HeLa cells fixed with 1% Paraformaldehyde and using CD44 Mouse mAb (168205,dilution 1:200,green). DAPI was used to stain nucleus(blue).

    Immunohistochemical analysis of paraffin-embedded human tonsils using CD44 (2H12) Mouse mAb.

    Immunohistochemical analysis of paraffin-embedded human tonsils using CD44 (2H12) Mouse mAb.

  • Background
    Swiss-Prot Acc.P16070.Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"