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Anti-CD44 (8E2) Mouse antibody

Cat.#: 168299

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Product Information

  • Product Name
    Anti-CD44 (8E2) Mouse antibody
  • Documents
  • Description
    CD44 (8E2) Mouse monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC
  • Species reactivity
    Human, Mouse
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant fragment of human CD44 (628-699) expressed in E. Coli.
  • Clonality
    Monoclonal
  • Formulation
    Ascitic fluid containing 0.03% sodium azide.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500 - 1/2000

    IHC: 1/200 - 1/1000

    ICC: 1/200 - 1/1000

    FC: 1/200 - 1/400

    ELISA: 1/10000

  • Validations

    Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using CD44 mouse mAb (dilution 1:100).

    Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using CD44 mouse mAb (dilution 1:100).

    Western blot detection of CD44 in COS7,HUVEC and Hela cell lysates using CD44 mouse mAb (dilution 1:1000).Predicted band size:82 Kda.Observed band size:82KDa.

    Western blot detection of CD44 in COS7,HUVEC and Hela cell lysates using CD44 mouse mAb (dilution 1:1000).Predicted band size:82 Kda.Observed band size:82KDa.

  • Background
    Swiss-Prot Acc.P16070.CD44, also known as IN, LHRMIC4, CDW44, HCELL. It is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"