-
Product Name
Human FDPS / Farnesyl Diphosphate Synthase (His Tag) recombinant protein
- Documents
-
Description
Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
-
Protein name
Farnesyl pyrophosphate synthase
-
Protein short names
MKIAA1293; FPP SYNTHASE; FARNESYL PYROPHOSPHATE SYNTHASE; FARNESYL PYROPHOSPHATE SYNTHETASE; 6E)-FARNESYL DIPHOSPHATE SYNTHASE; DIMETHYLALLYLTRANSTRANSFERASE; 6030492I17RIK; FDPSL1; FPS; AI256750; GERANYLTRANSTRANSFERASE; FPPS; FPP SYNTHETASE
-
Uniprot ID
P14324
-
Gene Name
FDPS; FPS; KIAA1293
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the human FDPS isoform b (NP_001129294.1) (Met 1-Lys 353) was expressed, with a polyhistide tag at the N-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human FDPS consisting of 368 amino acids and has a calculated molecular mass of 42.4 kDa. It migrates as an approximately 38 kDa band in SDS-PAGE under reducing conditions.
-
Purity
> 85 % as determined by SDS-PAGE
-
Validations
Human FDPS Protein (His Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"