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Product Name
Anti-FDPS Rabbit antibody
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Description
FDPS Rabbit monoclonal antibody
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Tested applications
WB, IHC-P, FC
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Species reactivity
Human
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Alternative names
FPS; FPPS; POROK9 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human FDPS
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000-1/5000
IHC: 1/20-1/100
FC: 1/20
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Validations
Western blot detection of FDPS in CHO-K1 cell lysates using FDPS Rabbit mAb(1:500 diluted).Predicted band size:48kDa.Observed band size:48kDa.
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Background
Swiss-Prot Acc.P14324.Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"