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Product Name
Anti-Cytokeratin 18 (2C3) Mouse antibody
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Description
Cytokeratin 18 (2C3) Mouse monoclonal antibody
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Tested applications
WB
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Species reactivity
Human, Mouse
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Isotype
IgG1
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Preparation
Antigen: Recombinant Protein of Keratin type I cytoskeletal 18
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Clonality
Monoclonal
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Formulation
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/500-1000
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Validations
Western blot detection of Keratin in Goat Muscle,CHO-K1,C6,Hela,3T3 cell lysates using Keratin 18 (2C3) Mouse mAb(1:1000 diluted).Predicted band size:46KDa.Observed band size:46KDa.
Western blot analysis of 1) Hela, 2) HepG2, 3) Mouse Skeletal Muscle tissue, (2F7) diluted at 1:1000.
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Background
Swiss-Prot Acc.P05783.Involved in the uptake of thrombin-antithrombin complexes by hepatic cells . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"