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Product Name
Rat B7-H4/B7S1/B7x (His Tag) recombinant protein
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Description
Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation (By similarity).
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Protein name
V-set domain-containing T-cell activation inhibitor 1
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Protein short names
BC032925; B7X; V-SET DOMAIN CONTAINING T-CELL ACTIVATION INHIBITOR 1; B7S1; T CELL COSTIMULATORY MOLECULE B7X; B7H4; IMMUNE COSTIMULATORY PROTEIN B7-H4
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Uniprot ID
Q501W4
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Gene Name
Vtcn1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat Vtcn1 (NP_001019415.1) (Phe29-Ser256) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat Vtcn1 consists 239 amino acids and predicts a molecular mass of 26.6 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Vtcn1 protein SDS-PAGE
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