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Product Name
VTCN1 antibody
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Description
VTCN1 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, A549 cells, HeLa cells, rat liver tissue. Observed molecular weight by Western-blot: 55-65 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
B7 H4 antibody; B7h.5 antibody; B7H4 antibody; B7S1 antibody; B7X antibody; FLJ22418 antibody; PRO1291 antibody; Protein B7S1 antibody; RP11 229A19.4 antibody; VCTN1 antibody; VTCN1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of VTCN1 recombinant protein (Accession Number: NM_001253849). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:116806(VTCN1 Antibody) at dilution of 1:600
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Background
VTCN1 also named B7H4, B7X, or B7S1 is a 282 amino acid protein, which contains 2 immunoglobulin-like domains and belongs to the immunoglobulin superfamily. VTCN1 negatively regulates T-cell mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 is a single-pass type I membrane protein, which is over-expressed in breast, ovarian, endometrial, renal cell and non-small-cell lung cancers. The molecular weight of VTCN1 is 31kDa, but mature VTCN1 is 50 to 80kDa glycosylated molecule with a 28kDa protein core.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"