VTCN1 antibody

Cat.#: 116806

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Product Information

  • Product Name
    VTCN1 antibody
  • Documents
  • Description
    VTCN1 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, A549 cells, HeLa cells, rat liver tissue. Observed molecular weight by Western-blot: 55-65 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    B7 H4 antibody; B7h.5 antibody; B7H4 antibody; B7S1 antibody; B7X antibody; FLJ22418 antibody; PRO1291 antibody; Protein B7S1 antibody; RP11 229A19.4 antibody; VCTN1 antibody; VTCN1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of VTCN1 recombinant protein (Accession Number: NM_001253849). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:116806(VTCN1 Antibody) at dilution of 1:600

    mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:116806(VTCN1 Antibody) at dilution of 1:600

  • Background
    VTCN1 also named B7H4, B7X, or B7S1 is a 282 amino acid protein, which contains 2 immunoglobulin-like domains and belongs to the immunoglobulin superfamily. VTCN1 negatively regulates T-cell mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 is a single-pass type I membrane protein, which is over-expressed in breast, ovarian, endometrial, renal cell and non-small-cell lung cancers. The molecular weight of VTCN1 is 31kDa, but mature VTCN1 is 50 to 80kDa glycosylated molecule with a 28kDa protein core.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"