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  • Phospho-GRIN1-S890 pAb

Phospho-GRIN1-S890 pAb

Cat.#: 166532

Special Price 232.3 USD

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Product Information

  • Product Name
    Phospho-GRIN1-S890 pAb
  • Documents
  • Description
    Polyclonal antibody to Phospho-GRIN1-S890
  • Tested applications
    WB
  • Species reactivity
    Human, Rat
  • Alternative names
    GRIN1 antibody; GluN1 antibody; MRD8 antibody; NMD-R1 antibody; NMDA1 antibody; NMDAR1 antibody; NR1 antibody; glutamate receptor ionotropic, NMDA 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A phospho specific peptide corresponding to residues surrounding S890 of human GRIN1
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - Phospho-GRIN1-S890 pAb

    Western blot - Phospho-GRIN1-S890 pAb

    Western blot analysis of extracts of C6 cells, using Phospho-GRIN1-S890 antibody at 1:1000 dilution. C6 cells were treated by PMA/TPA (200nM) for 30 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit .Exposure time: 90s.

  • Background
    Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"