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Product Name
Phospho-GRIN1-S896 pAb
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Description
Polyclonal antibody to Phospho-GRIN1-S896
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
GRIN1 antibody; GluN1 antibody; MRD8 antibody; NMD-R1 antibody; NMDA1 antibody; NMDAR1 antibody; NR1 antibody; glutamate receptor ionotropic, NMDA 1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A phospho specific peptide corresponding to residues surrounding S896 of human GRIN1
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - Phospho-GRIN1-S896 pAb
Western blot analysis of extracts from mouse Brain tissue, using phospho-GRIN1-S896 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.
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Background
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"