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Product Name
GRIN1 Polyclonal Antibody
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Description
Polyclonal antibody to GRIN1
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Tested applications
IHC, IF
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Species reactivity
Human, Rat
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Alternative names
GRIN1 antibody; GluN1 antibody; MRD8 antibody; NMD-R1 antibody; NMDA1 antibody; NMDAR1 antibody; NR1 antibody; glutamate receptor ionotropic, NMDA 1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human GRIN1
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IHC 1:50 - 1:200
IF 1:50 - 1:200 -
Validations
Immunohistochemistry - GRIN1 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat brain using GRIN1 Antibody at dilution of 1:100 (40x lens).
Immunofluorescence - GRIN1 Polyclonal Antibody
Immunofluorescence analysis of U2OS cells using GRIN1 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Background
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"