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  • Mouse LAG3 recombinant protein (C-human IgG1-Fc)

Mouse LAG3 recombinant protein (C-human IgG1-Fc)

Cat.#: 514907

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Product Information

  • Product Name
    Mouse LAG3 recombinant protein (C-human IgG1-Fc)
  • Documents
  • Description
    LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells. It also acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo.Immune Checkpoint
    Immune Checkpoint Targets Co-inhibitory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
  • Protein name
    Lymphocyte activation gene 3 protein
  • Protein short names
    CD223,LAG-3,Ly66
  • Uniprot ID
    Q61790
  • Gene Name
    Lymphocyte activation gene 3 protein; LAG-3; CD antigen CD223
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse LAG3 (NP_032505.1) (Met1-Arg432) was expressed with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse LAG3 consists of 647 amino acids and predicts a molecular mass of 71 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Validations

    Mouse LAG3/LAG-3/CD223 Protein 14960

    Mouse LAG3/LAG-3/CD223 Protein 14960

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"