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Human LAG3 / CD223 / Lymphocyte activation gene 3 (His Tag) recombinant protein

Cat.#: 503410

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Product Information

  • Product Name
    Human LAG3 / CD223 / Lymphocyte activation gene 3 (His Tag) recombinant protein
  • Documents
  • Description
    LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells. It also acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo.
  • Protein name
    Lymphocyte activation gene 3 protein
  • Protein short names
    LYMPHOCYTE-ACTIVATION GENE 3; LY66; LAG-3; LYMPHOCYTE ACTIVATION GENE 3 PROTEIN; LAG3; CD223
  • Uniprot ID
    P18627
  • Gene Name
    LAG3; FDC
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human LAG3 (NP_002277.4) (Met1-Leu450) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human LAG3 consists of 433 amino acids and predicts a molecular mass of 47 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Validations

    Human LAG3 / CD223 / Lymphocyte activation gene 3 Protein (His Tag)

    Human LAG3 / CD223 / Lymphocyte activation gene 3 Protein (His Tag)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"